Salvage MR-guided High-Dose-Rate Brachytherapy for Prostate Bed Recurrence After Radiotherapy in the PSMA PET Scan Era
Status: Recruiting
Location: See location...
Intervention Type: Radiation
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This is an interventional, single-centre, single-arm, non-randomized, prospective, feasibility trial investigating salvage MR-guided High-Dose-Rate brachytherapy for prostate bed recurrence after postoperative radiotherapy.
Eligibility
Participation Requirements
Sex: Male
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients who received previous RT to the prostate bed +/- pelvic nodal regions
• Prostate-bed recurrence identified by biopsy and/or MRI and/or PSMA-PET scan
• At least two continuous PSA elevations post RT and PSA above 0.2 ng/dl
• With or without ADT PSA doubling time from nadir greater than 6 months
• ECOG 0-2
• Age greater than 18 years
Locations
Other Locations
Canada
Princess Margaret Cancer Centre
RECRUITING
Toronto
Contact Information
Primary
Peter Chung, MD
peter.chung@uhn.ca
416-946-4501
Time Frame
Start Date: 2024-08-08
Estimated Completion Date: 2031-03-01
Participants
Target number of participants: 20
Treatments
Experimental: 2xHDR Brachytherapy
Salvage MR-guided High-Dose-Rate Brachytherapy for Prostate Bed recurrence after Postoperative Radiotherapy.
Related Therapeutic Areas
Sponsors
Leads: University Health Network, Toronto